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Bruce Levin, Ph.D.
Key Collaborator

Dr. Levin is Professor and Chair of the Department of Biostatistics at Columbia University’s Mailman School of Public Health. He is the senior statistical consultant on several multicenter randomized clinical trials in the field of neurology and cardiology, including the WARCEF trial funded by NINDS (Warfarin versus Aspirin in Reduced Cardiac Ejection Fraction), the TNK trial (Tenecteplase versus rt-PA in acute stroke) and the QALS trial for ALS patients. He serves as the Director of the Statistics, Epidemiology, and Data Management (SED) Core of the HIV Center. Dr. Levin has a long-standing interest in statistical methodology for clinical trials, public health, and the law. Using sequential statistical methods, he has published on innovative trial designs, e.g., designs that minimize ethical costs, designs that emphasize the selection paradigm rather than the hypothesis test paradigm, and phase II trials that combine a selection phase with a non-superiority (futility) phase utilizing the same data.

Dr. Levin is a Fellow of the American Statistical Association. He has recently published the 3rd edition of Statistical Methods for Rates and Proportions with Myunghee Cho Paik and the late Joseph L. Fleiss. Dr. Levin served for ten years as Consulting Statistical Editor for the American Journal of Public Health. He has also served as an expert statistical witness in many court cases, and is co-author with Michael O. Finkelstein of Statistics for Lawyers, now in its second edition. He currently co-edits the column “Chance at the Bar” for Chance magazine, the popular journal of the American Statistical Association.

Areas of expertise
Biostatistics: Categorical data analysis, conditional likelihood analysis, logistic regression, clinical trials methods, sequential experimentation, empirical Bayes methods, reproductive epidemiology, statistics in the law, statistics and bioethics.

Selected recent publications
Leu C-S, Levin B. (2006) A Generalization of the Levin-Robbins Procedure for Binomial Subset Selection and Recruitment Problems. Statistica Sinica (in press).

Finkelstein MO, Levin B, McKeague IW, Tsai W-Y. (2006) A Note on the Censoring Problem in Empirical Case-Outcome Studies. J Empirical Legal Studies 3(2):375-395.

Levy G, Kaufmann P, Buchsbaum R, Montes J, Barsdorf A, Arbing R, Battista V, Zhou X, Mitsumoto H, Levin B, Thompson JLP. (2006) A Two-Stage Design for a Phase II Clinical Trial of Coenzyme Q10 in ALS. Neurology 66:660-663.

Levin B, Finkelstein MO. (2005) Compositional Analysis of Bullet Lead as Forensic Evidence. Journal of Law and Policy 13(1):119-142.

Fleiss JL, Levin B, Paik MC. (2003) Statistical Methods for Rates and Proportions, third edition. New York: Wiley.

Finkelstein MO, Levin B. (1990) Statistics for Lawyers. New York: Springer–Verlag. Second edition October 2001.